https://test.indicwiki.in/index.php?action=history&feed=atom&title=Template%3AInfobox_drug%2FELbox 2026-10-31T09:08:59Z Revision history for this page on the wiki MediaWiki 1.36.1 https://test.indicwiki.in/index.php?title=Template:Infobox_drug/ELbox&diff=10449&oldid=prev 2022-05-23T05:07:22Z

<p>Created page with &quot;{{Infobox drug | INN = acetylsalicylic acid | BAN=Aspirin | USAN=Aspirin | Watchedfields = changed | verifiedrevid = 464364671 | IUPAC_name = 2-(ethyloxy)benzenecarboxylic aci...&quot;</p> <p><b>New page</b></p><div>{{Infobox drug<br /> | INN = acetylsalicylic acid<br /> | BAN=Aspirin<br /> | USAN=Aspirin<br /> | Watchedfields = changed<br /> | verifiedrevid = 464364671<br /> | IUPAC_name = 2-(ethyloxy)benzenecarboxylic acid<br /> | image = Aspirin-skeletal.svg<br /> | image2 = Aspirin-B-3D-balls.png<br /> | width = 100px<br /> | width2 = 125px<br /> &lt;!--Clinical data--&gt;<br /> | pronounce = acetylsalicylic acid {{IPAc-en|ə|ˌ|s|iː|t|əl|ˌ|s|æ|l|ᵻ|ˈ|s|ɪ|l|ᵻ|k}}<br /> | Drugs.com = {{drugs.com|monograph|aspirin}}<br /> | MedlinePlus = a682878<br /> | licence_US = Aspirin<br /> | pregnancy_AU = C<br /> | pregnancy_US = C<br /> | pregnancy_US_comment= D in the 3rd trimester<br /> | legal_AU = S2<br /> | legal_AU_comment = except when given intravenously (in which case it is schedule 4), used in animal medicine (schedule 5/6) or when the dose is higher than usual.<br /> | legal_UK = GSL<br /> | legal_US = OTC<br /> | routes_of_administration = by mouth, rectal, lysine acetylsalicylate may be given [[intravenous therapy|intravenously]] or [[intramuscular injection|intramuscularly]]<br /> &lt;!--Pharmacokinetic data--&gt;<br /> | bioavailability = 80–100%&lt;ref name=MSR&gt;{{cite web|title=Zorprin, Bayer Buffered Aspirin (aspirin) dosing, indications, interactions, adverse effects, and more|work=Medscape Reference|publisher=WebMD|access-date=3 April 2014|url=http://reference.medscape.com/drug/zorprin-bayer-buffered-aspirin-343279#showall|url-status=live|archive-url=https://web.archive.org/web/20140407080151/http://reference.medscape.com/drug/zorprin-bayer-buffered-aspirin-343279#showall|archive-date=7 April 2014|df=dmy-all}}&lt;/ref&gt;<br /> | protein_bound = 80–90%&lt;ref name = MD&gt;{{cite web|title=Aspirin|work=Martindale: The Complete Drug Reference|publisher=Pharmaceutical Press|date=14 January 2014|access-date=3 April 2014|url=http://www.medicinescomplete.com/mc/martindale/current/2601-s.htm|editor=Brayfield, A}}&lt;/ref&gt;<br /> | metabolism = [[Liver]], ([[CYP2C19]] and possibly [[CYP3A]]), some is also hydrolysed to salicylate in the gut wall.&lt;ref name = MD/&gt;<br /> | elimination_half-life = Dose-dependent; 2 h to 3 h for low doses, 15 h to 30 h for large doses.&lt;ref name = MD/&gt;<br /> | excretion = Urine (80–100%), sweat, saliva, feces&lt;ref name = MSR/&gt;<br /> &lt;!--Identifiers--&gt;<br /> | IUPHAR_ligand = 4139<br /> | CAS_number_Ref = {{cascite|correct|??}}<br /> | CAS_number = 50-78-2<br /> | ATC_prefix = A01<br /> | ATC_suffix = AD05<br /> | ATC_supplemental = {{ATC|B01|AC06}}, {{ATC|N02|BA01}}<br /> | PubChem = 2244<br /> | DrugBank_Ref = {{drugbankcite|correct|drugbank}}<br /> | DrugBank = DB00945<br /> | ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}<br /> | ChemSpiderID = 2157<br /> | UNII_Ref = {{fdacite|correct|FDA}}<br /> | UNII = R16CO5Y76E<br /> | KEGG_Ref = {{keggcite|correct|kegg}}<br /> | KEGG = D00109<br /> | ChEBI_Ref = {{ebicite|correct|EBI}}<br /> | ChEBI = 15365<br /> | ChEMBL_Ref = {{ebicite|correct|EBI}}<br /> | ChEMBL = 25<br /> | PDB_ligand = AIN<br /> &lt;!--Chemical data--&gt;<br /> | C=9 <br /> | H=8 <br /> | O=4<br /> | molecular_weight = 180.157 g/mol<br /> | smiles = O=C(C)Oc1ccccc1C(=O)O<br /> | StdInChI_Ref = {{stdinchicite|correct|chemspider}}<br /> | StdInChI = 1S/C9H8O4/c1-6(10)13-8-5-3-2-4-7(8)9(11)12/h2-5H,1H3,(H,11,12)<br /> | StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}<br /> | StdInChIKey = BSYNRYMUTXBXSQ-UHFFFAOYSA-N<br /> | synonyms = 2-acetoxybenzoic acid&lt;br /&gt;acetylsalicylate&lt;br /&gt;acetylsalicylic acid&lt;br /&gt;O-acetylsalicylic acid<br /> | density = 1.40<br /> | melting_point = 135<br /> | boiling_point = 140<br /> | boiling_notes = (decomposes)<br /> | solubility = 3<br /> }}</div>

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